CSF & PK SAMPLING

Lotus is able to perform specialized studies requiring PK & CSF Sampling (both intermittent and continuous)

Understanding the distribution of pharmaceutical agents in the central compartment is important for many pharmaceutical products. At Lotus, we have performed several studies that have required continuous or intermittent CSF sampling. Continuous sampling is achieved by placing a multi‐orifice catheter in the patient’s intrathecal space. We have sampled continuously for up to 72 hours.

Click here to view recent publication on CSF Kinetics Intravenous of Acetaminophen